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Breaking Free: Overcoming Alcohol Addiction with the Sinclair Method

Breaking Free: Overcoming Alcohol Addiction with Pharmacotherapy and the Sinclair Method

For many people, having a drink or two is a regular part of socializing, celebrating, or unwinding after a long day. However, approximately 15 million adults in the United States struggle with alcohol use disorder (AUD), a condition that involves compulsive drinking, withdrawal symptoms, and negative consequences on various aspects of life.

Alcohol addiction is a chronic brain disease that requires professional help and ongoing support to manage and recover from. In this article, we will explore two important aspects of alcohol addiction: personal experiences with attempts to moderate drinking, and the use of pharmacotherapy and the Sinclair Method to overcome AUD.

Early Dislike of Alcohol

Some people have had negative experiences with alcohol early in life, or simply do not enjoy its taste, effects, or social context. They may feel pressured to drink to fit in or cope with stress, but find that alcohol makes them feel worse, sick, or out of control.

In my case, I never liked the taste of beer, wine, or spirits, and preferred soft drinks or water when hanging out with friends. However, I also noticed that some of my social activities revolved around drinking, such as going to bars, clubs, or parties, and I felt like I was missing out on some fun.

So, I started trying different types of alcohol, hoping to find one that would make me feel more comfortable and confident. Unfortunately, I soon discovered that alcohol did not really change my personality or mood in a positive way, and sometimes caused me to say or do things I regretted later.

I also experienced unpleasant hangovers, disrupted sleep, and a general sense of unease or guilt. As a result, I decided that alcohol was not worth the effort and risk, and chose to abstain from it as much as possible.

Of course, this was not always easy, especially when I was in situations where drinking seemed expected or encouraged. However, I learned to be firm and assertive about my decision to not drink, and to find other ways to have fun and connect with people.

Relationship with an Alcoholic and Heavy Drinking

Other people may have a different kind of relationship with alcohol, one that involves being intimately involved with someone who is struggling with AUD or engaging in excessive or harmful drinking themselves. This can be a complicated and stressful situation, as the person may feel torn between love, loyalty, and self-preservation.

In my case, I dated someone who drank heavily and frequently, and who sometimes became verbally and physically abusive when drunk. At first, I tried to excuse or dismiss his behavior, thinking that he was just stressed or upset, or that he would change if I loved him enough.

However, as time passed, I realized that his drinking was not just a problem for him, but for me and our relationship too. I felt like I was walking on eggshells, constantly fearing his outbursts, blaming myself for his anger, and sacrificing my own needs and goals.

Moreover, I started to notice that I was also drinking more than I normally would, using alcohol as a way to cope with the stress and anxiety. That’s when I realized that I had to make a change, for my own sake.

I broke up with him, started therapy to deal with the trauma and codependency, and began to explore ways to manage my own drinking tendencies.

Attempts to Moderate Drinking

Many people who struggle with AUD may attempt to reduce or control their drinking, either on their own or with the help of support groups, counseling, or medication. However, moderating drinking can be challenging, as it requires not only willpower and discipline, but also addressing underlying emotional, cognitive, and social factors that contribute to the addiction.

For me, despite my initial reluctance to drink, I found that I was susceptible to cravings and relapses, especially when I was stressed, bored, or lonely. I tried to use strategies such as setting limits, pacing myself, alternating alcoholic beverages with non-alcoholic ones, and avoiding triggers, but I found that these methods were not effective in the long term.

I still felt like I was missing out, and that my life would be more exciting or enjoyable if I just let go and indulged in alcohol. That’s when I started to explore the possibility of using pharmacotherapy, a type of treatment that involves using medication to assist with recovery from addiction.

Definition and Explanation of Pharmacotherapy

Pharmacotherapy, also known as medication-assisted treatment (MAT), is a form of addiction treatment that involves using prescription drugs to reduce cravings, withdrawal symptoms, and relapse risk. The goal of pharmacotherapy is to help people with AUD achieve and maintain long-term abstinence or harm reduction, by addressing the biological and psychological aspects of addiction.

There are various types of medications that can be used for AUD, depending on the person’s medical history, preferences, and treatment goals. Some of the most common medications are:

– Disulfiram (Antabuse): Causes severe physical reactions when alcohol is consumed, such as nausea, vomiting, headache, and flushing.

Encourages abstinence. – Acamprosate (Campral): Stabilizes brain chemistry and reduces craving by mimicking the effects of GABA, a neurotransmitter involved in relaxation.

Can be taken daily or in anticipation of drinking. – Naltrexone (ReVia, Vivitrol): Blocks the effects of alcohol on the brain’s reward system, thereby reducing the pleasurable sensations and reinforcing behaviors associated with drinking.

Can be taken orally or via injection. – Topiramate (Topamax): Regulates brain activity and reduces craving and impulsivity by enhancing the effects of GABA and inhibiting the effects of glutamate, another neurotransmitter involved in excitability.

Can also be used for other conditions, such as migraines and the Sinclair Method

One of the latest and most promising forms of pharmacotherapy for AUD is the Sinclair Method (TSM), a protocol developed by Dr. John Sinclair, a behavioral psychologist, in the 1990s. The Sinclair Method involves using the medication naltrexone in a targeted dosing regimen, which means taking the pill one hour before drinking, but not on days when alcohol is not consumed.

The rationale behind TSM is based on the theory that addiction is caused by learned behavior that is reinforced by the release of endorphins, the brain’s natural opioids, when alcohol is consumed. Endorphins create a sense of pleasure and reward, and over time, the brain associates alcohol with those feelings, leading to stronger and more frequent cravings.

Naltrexone works by blocking the receptors in the brain that respond to endorphins, thereby reducing the pleasure and reward associated with drinking, and gradually changing the neural pathways that lead to addiction. TSM can be done in a self-directed manner, using online resources and support groups, or with the help of a healthcare provider who specializes in addiction medicine or psychiatry.

Personal Experience with Pharmacotherapy and TSM

As someone who was skeptical about taking medication for personal reasons, I was hesitant to try pharmacotherapy at first. However, after researching and consulting with a doctor who explained the benefits and risks of different medications, I decided to give TSM a chance.

I obtained a prescription for naltrexone and started taking it one hour before drinking, as instructed. At first, I did not notice any significant changes in my drinking patterns or cravings, but after a few weeks, I began to feel less interested in alcohol overall.

I still drank occasionally, but I found that I did not enjoy it as much as before, and did not feel the same sense of satisfaction or anticipation. I also noticed that I was able to say no to offers of alcohol more easily, and did not feel as anxious or restless when I abstained.

Over time, I found that my drinking decreased gradually, and that I no longer felt the need or desire to use alcohol as a coping mechanism. Moreover, I began to explore other activities and hobbies that I had neglected or forgotten, such as reading, hiking, and volunteering.

TSM was not a cure-all for my addiction, but it was a catalyst for transformation that allowed me to regain control of my life, one step at a time.


In conclusion, alcohol addiction is a complex and pervasive condition that affects millions of people worldwide. However, recovery is possible with the right treatment and support.

Personal experiences with attempts to moderate drinking can be insightful and relatable, and provide encouragement for others who are struggling with the same issues. Pharmacotherapy and the Sinclair Method offer promising and evidence-based options for managing and overcoming AUD, by addressing the brain chemistry and learned behavior that underlie addiction.

It is important to remember that pharmacotherapy is not a panacea, and that individual differences in biology, psychology, and environment can affect its effectiveness. Therefore, seeking professional advice and guidance is crucial when considering whether or not to use medication for alcohol addiction.

Nonetheless, pharmacotherapy and the Sinclair Method are worthy of consideration and exploration, as a way to break free from the grip of alcohol addiction, and reclaim one’s health, happiness, and purpose.

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